Screen Shot 2022-10-31 at 15.17.40Prelecionista: Rosiane Fátima de Almeida
Orientador: Acelino Couto Alfenas
Data: 01/11/2022, às 16h, no anfiteatro ESB

Epigenetics is the study of changes in gene function that are inheritable and occur independently of changes in DNA sequence. This concept has been debated by the scientific community over the last years. The most advanced research in this field is focused on the inheritance of traits associated with the occurrence of diseases such as autism, diabetes, obesity, and cancer. In plants, epigenetic mechanisms influence the first level of gene expression regulation, that is, the control of the degree of chromatin compaction. To maintain DNA stability, the most studied mechanism is DNA methylation, which is associated with increased chromatin compaction and silencing of transposable elements. According to studies of transgenerational-acquired disease resistance, the dynamics of methylation or demethylation of transposable elements can affect the expression of defense genes beyond one generation. Furthermore, DNA methylation can result in the formation of epialleles or alleles, which can have an evolutionary impact on pathogen-host relationships.